Decoding Weight Loss: GLP-1 Drugs, Root Causes, and Comprehensive Health Strategies
Health Decoded
Unlock your full human potential with the Health Decoded podcast as hosts Dr. Alessi and Matt Tack break down the truth about all things health and empower you to take charge of your well-being.
Dr. Alfred AlessiMatt Tack

Decoding Weight Loss: GLP-1 Drugs, Root Causes, and Comprehensive Health Strategies

S3 E31 • Aug 5, 2025 • 39 mins

In this episode, Matt Tack and Dr. Alfred Alessi introduce the Alessi Total Care Program, tackling frustrations with medications and the rise of GLP-1 drugs for weight loss. They discuss obesity's root causes, including hormonal impacts, sleep, circadian rhythms, and metabolic health. The episode examines toxic burden, inflammation, and gut health in weight management. It explores appetite suppressants, metabolic reeducation, and personalized approaches with testing, nutrition, and exercise. Strategies like detox, peptide therapy, and nervous system support are also discussed, concluding with insights into the Alessi Total Care Program.

Key Points

  • Suppressing hunger with medication doesn't address the root causes of weight gain such as insulin resistance, hormone imbalances, and gut health.
  • Long-term weight loss and metabolic health require a comprehensive approach that includes personalized nutrition, strategic movement, gut restoration, and nervous system support.
  • Medications like Ozempic can lead to muscle loss, slowed metabolism, and other health risks if not paired with lifestyle changes and functional medicine strategies.
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