Personalized Health: Genetics, Nutrigenetics, and Lifestyle Optimization
S4 E54 • Jan 27, 2026 • 28 minsIn this episode, Dr. Alfred Alessi delves into the role of peptides in managing inflammation and introduces the concept of nutrigenetic testing. The discussion covers the influence of genetics and epigenetics on health, emphasizing the importance of personalizing supplements and lifestyle choices tailored to genetic profiles. Key indicators of impaired genetic nutrient pathways are explored, with an overview of the NutraPro genetic panel and its clinical applications. The conversation highlights the personalization of diet and exercise based on genetic predispositions. The episode concludes with insights into Ascend Functional Health and special offers, along with encouragement for listener engagement.
Hormone Replacement Therapy: Balancing Health, Longevity, and Optimization
S4 E53 • Jan 22, 2026 • 13 minsIn this episode, explore the complexities of hormone replacement therapy, beginning with an introduction to its principles. The discussion differentiates between testosterone replacement and optimization, highlighting the benefits of testosterone optimization therapy. Risks associated with testosterone abuse are addressed, emphasizing the importance of proper management. The role of hormones in health and longevity is examined, with a focus on hormone replacement therapy for women and its unique considerations. The episode concludes with key takeaways, summarizing the critical points discussed and their implications for overall well-being and longevity.
Corporate Wellness Unveiled: Dr. Jim Horning's and his Strategies for a Healthier Workforce
S4 E52 • Jan 13, 2026 • 27 minsIn this episode, Dr. Jim Horning joins Matt Tack to discuss the significance of corporate wellness programs. The conversation begins with an overview of why these programs matter, followed by an exploration of the challenges faced during implementation. Effective strategies for wellness initiatives are shared, highlighting their impact on insurance and company culture. The discussion identifies the target audience for corporate wellness and examines the scalability of wellness solutions. The episode concludes with a summary of the benefits of a healthy workforce and encourages listener engagement for further insights.
Unlocking Longevity: DEXA Scans and the Path to Optimal Health
S4 E51 • Jan 6, 2026 • 30 minsIn this episode, Matt Tack and Dr. Alessi explore the significance of muscle as a vital asset and the importance of DEXA scans for health and longevity. They discuss their clinic's expansion and enhanced services, focusing on DEXA's accuracy in measuring visceral fat, lean muscle mass, and bone density. Longevity strategies, inflammation, metabolic disorder prevention, and real-time DEXA insights are examined. They also delve into advanced testing in hormones, gut health, and micronutrients, alongside a partnership with Apex Labs for supplement quality. The episode highlights personalized strength programs, in-house DEXA scanning, and concludes with special offers.
Peptide Power: Exploring Healing, Longevity, and Wellness Solutions
S4 E50 • Dec 25, 2025 • 15 minsIn this episode, delve into the world of peptides with an overview of their functions and benefits. Explore BPC 157, known as the repair peptide, and TB 500, a system healing accelerator. Discover the longevity and regeneration potential of GHK-Cu and the inflammation and gut-regulating properties of KPV. The discussion also covers the peptide blend of CJC 1295 and Ipamorelin, highlighting their combined benefits. The episode concludes with closing remarks and holiday wishes, offering insights into how peptides can be integrated into health practices for enhanced well-being.
Inflammation Unveiled: Understanding, Detecting, and Combating Chronic Inflammation
S4 E49 • Dec 16, 2025 • 30 minsIn this episode, explore the complexities of inflammation with Dr. Alessi and Matt Tack. They differentiate between types of inflammation and discuss how modern lifestyles contribute to chronic inflammation and its health impacts. The hidden nature of inflammation and the limitations of healthcare in addressing it are examined, followed by methods for detecting and reversing chronic inflammation. Strategies to combat inflammation through nutritional assessments and genetic testing are highlighted. The discussion also emphasizes the connection between chronic disease and inflammation. The episode concludes with information on connecting with Health Decoded and closing remarks.
From Burnout to Balance: Dmitri George's Guide to Tailored Fitness and Lasting Health
S4 E48 • Dec 2, 2025 • 49 minsIn this episode, Dr. Alessi and Dmitri George discuss Dmitri's transition from a corporate career to fitness training. They explore his approach to client customization and the role of trainers in initial assessments. The conversation covers the integration of physical activity with resistance training and the importance of consistent nutritional habits, while highlighting common exercise mistakes. Psychological aspects of burnout and recovery are examined, alongside debunking health misinformation on social media. Topics include creating positive health habits, gut health's impact on wellness, and tailoring fitness programs to individual needs. The episode concludes with insights on involving family in health practices and viewing health as an investment.
Holiday Health Hacks: Nutrition, Sleep, and Stress Management for a Joyful Season
S4 E47 • Nov 25, 2025 • 32 minsIn this episode, explore the significance of maintaining health during the holiday season. Learn strategies for healthier eating and stress management, and understand how sleep and hormones influence holiday eating habits. Discover how to avoid the "I'll start in January" mentality with a blueprint for a healthy holiday plate and strategic shopping tips. Gain insights into eating strategically at parties and maintaining blood sugar control. Emphasizing health as a continuous journey, the episode delves into personalized nutrition, using blood and gut tests, and genetic markers for tailored dietary benefits. Biohacks and functional medicine tips offer a robust plan for holiday health, concluding with a call to action and closing remarks.
Biohacking and Beyond: Advanced Health Strategies and Daily Optimization Tips
S4 E46 • Nov 18, 2025 • 34 minsIn this episode, Carter West discusses his biohacking journey with Dr. Alfred Alessi, who advocates for proactive healthcare. They explore biohacking vs. bio harmonizing, focusing on sleep optimization, affirmations, and the influence of self-image on health. Additional topics include daytime optimization, therapeutic testosterone, methylene blue, red light therapy, inflammation, nutrition, seed oils, workout efficiency, and maintaining routines while traveling. They also delve into neuroplasticity through language learning. The episode wraps up with an introduction to Alessi Functional Health services and next steps for listeners.
Optimizing Health: Hormones, Stress, and the Path to Vitality
S4 E45 • Nov 11, 2025 • 35 minsIn this episode, explore the pivotal role of change in health with an exclusive offer for Health Decoded listeners. Dr. Alfred Alessi discusses hormones' impact on vitality, daily stressors, and their health implications. Learn about core restoration as a precursor to hormone therapy and comprehensive functional testing. Delve into therapeutic testosterone, hormone replacement, and bioidentical hormones. Discover the importance of data in distinguishing normal from optimized health. Listener engagement is encouraged through Q&A submissions. The episode wraps up with closing remarks and gratitude.
Integrative Health Insights: Chiropractic Care, Sleep Optimization, and Holistic Wellness Tips
S4 E44 • Nov 4, 2025 • 31 minsIn this episode, Dr. Alfred Alessi introduces the Total Care Program before welcoming Dr. Carter West to discuss chiropractic education and his family's chiropractic legacy. They explore integrative therapies in chiropractic care and the role of integrative health practices, including naturopathy and blood work analysis. Dr. West uses car analogies to explain health care approaches and reflects on Dr. Alessi's influence. Dr. Alessi shares lifestyle tips for mental health, emphasizing sleep optimization and hygiene, work-life balance, and biohacks like nasal breathing. Listener questions are addressed, and the episode concludes with a wrap-up and call to action.
Longevity Unlocked: Building Strength, Resilience, and Healthy Aging Habits
S4 E43 • Oct 28, 2025 • 20 minsIn this episode, Matt Tack introduces the concept of longevity and its significance in health. He explores the pillars of longevity and discusses the aging decay curve, emphasizing the importance of muscle mass and different training types for promoting long life. The episode delves into cognitive and emotional resilience as key factors in aging well. Matt shares practical tips for enhancing longevity, including the importance of hydration, adequate sleep, and maintaining consistency in health routines. A weekly challenge is presented to listeners, encouraging them to implement these strategies. The episode concludes with closing remarks and a call to action.
Health Momentum: Unlocking 1% Daily Health Gains, Quarterly Challenges, and Progress Over Perfection
S4 E42 • Oct 21, 2025 • 11 minsIn this episode, Matt Tack introduces listeners to the MAPS training method, emphasizing the value of self-competition in personal health journeys. The discussion highlights the power of compounding health benefits and the importance of tracking metrics. Matt outlines quarterly health challenges, such as a gut reset and a strength phase, providing listeners with actionable steps to enhance their well-being. Tips for navigating health during the holiday season are shared, underscoring the takeaway message of prioritizing progress over perfection. The episode wraps up with closing remarks and a call to action for listeners to engage with their health goals.
Gut Health Decoded: Probiotics, Dysbiosis, and Unlocking Your Microbiome's Potential
S3 E41 • Oct 14, 2025 • 25 minsIn this episode, Dr. Alfred Alessi goes in-depth on the critical role of probiotics in maintaining gut health and the importance of advanced testing to uncover hidden imbalances. They explore the key players in the gut microbiome and the potential dangers posed by pathobionts and pathogens. The discussion highlights the connections between dysbiosis and chronic health issues, emphasizing the importance of recognizing leaky gut markers. Sponsored by Alessi Functional Health, the episode provides insights into functional markers and digestive health. Listeners are guided on actionable steps from their personalized gut health reports and accessing their gut health scores. The episode concludes with closing thoughts and contact information.
Debunking Wellness: Gut Health, Nutrition, and Thriving with Dr. Anya Szigeti
S3 E40 • Oct 7, 2025 • 52 minsIn this episode, Dr. Alfred Alessi and Dr. Anya Szigeti delve into the complexities of IBS and its diagnosis. Dr. Szigeti shares her background in functional medicine and discusses the impact of healthy fats, sleep, and gut health on thyroid function. They explore patient care, diagnostic testing, and the Zigeti Method. The conversation shifts to mindset, sleep hygiene, and health optimization, highlighting insights from Dr. Szigeti's new book on health and diet. Gender differences in fasting, personalized nutrition, and protein's role in diet are examined. The importance of fiber and optimal health markers are emphasized. The episode concludes with Dr. Szigeti's upcoming projects and contact information.
Longevity Unveiled: Early Warning Signs, Lifestyle Choices, and Functional Medicine Approaches
S3 E39 • Sep 30, 2025 • 35 minsIn this episode, Dr. Alfred Alessi discusses recognizing health warning signs and their impact on longevity. They explore insights from blue zones, the genetics vs. lifestyle debate, and early aging red flags. The role of environment and lifestyle in aging is examined, with a focus on testing and tracking for longevity. They highlight functional medicine's view on metabolic health, muscle mass, and body composition. The episode compares advanced longevity testing options and discusses conventional and functional approaches, including regenerative therapies. It concludes with thoughts on enhancing longevity and encourages listener interaction.
Thyroid Health Decoded: Weight, Function, and Healing with Functional Medicine
S3 E38 • Sep 23, 2025 • 24 minsIn this episode, Dr. Alfred Alessi goes into the connection between thyroid function and weight management. They discuss the thyroid gland's role in the HPT axis and how dysfunction affects weight. A case study underscores the risks of misdiagnosis and the need for thorough testing. Common symptoms are highlighted as vital warning signs. Sponsored by Alessi Functional Health's six R gut healing protocol, the episode stresses comprehensive testing in functional medicine. Practical tips for eliminating thyroid triggers and lifestyle changes are shared. Personalized assistance from Alessi Functional Health is available, encouraging listener engagement.
Foundational Health Habits: Overcoming Quick Fixes and Building Lasting Wellness
S3 E37 • Sep 16, 2025 • 19 minsIn this episode, Matt Tack talks about the importance of foundational health habits over quick fixes, exploring the limitations of popular diet shows like "The Biggest Loser." They discuss why habits are crucial for long-term health and address the role of inflammation in health and longevity. The episode highlights the use of GLP-1 medications and emphasizes healing from the inside out. Insights from "Atomic Habits" and the Alessi Total Care Program are shared to enhance habit formation. The episode is sponsored by the Repair, Clear, and Thrive challenge and concludes with closing remarks and a call to action for listeners.
Healing from Within: The Gut Health Connection and Functional Medicine Insights
S3 E36 • Sep 9, 2025 • 32 minsIn this episode, Dr. Alfred Alessi goes into the foundations of functional medicine, beginning with an introduction to the new "Repair, Clear, and Thrive" challenge. They explore the complexities of gut health, emphasizing the microbiome's intricate functions and its vulnerability to modern life's impacts. The discussion highlights symptoms of gut dysfunction and the role of functional medicine testing in identifying these issues. Key topics include tests for gut dysfunction and the Five R gut healing protocol, which underscores gut healing as an ongoing process. The episode concludes by linking gut health to overall well-being, offering insights into foundational health practices.
Repair, Clear, and Thrive: Building Health and Community
S3 E35 • Sep 2, 2025 • 25 minsIn this episode, Matt Tack and Dr. Alfred Alessi introduce the "Repair, Clear, and Thrive" challenge, spotlighting its role in promoting holistic health. They share updates on their clinic's expansion, new treatments, and the three pillars of health. The discussion highlights the importance of health professionals leading by example and introduces new clinic services. The episode delves into the challenge's social aspects and its potential for community building. A preview of future content sets the stage for upcoming episodes, while listeners are encouraged to engage by liking, subscribing, and sharing. Health resources and newsletter information are provided, concluding with expressions of gratitude.


